3 (2006): 899-906, 18.https://pubchem.ncbi.nlm.nih.gov/compound/Suramin-sodium. Having said that, we can do a lot more about it than simply sitting around and waiting to see who is harmed or dies. "Suramin: an anticancer drug with a unique mechanism of action. 19. Suramin sodium (suramin) dosing, indications, interactions - Medscape i'm not sure why i'm saying that med, but for some reason it came up in my research around suramin alternatives. Any natural medicine with 0.01% of these deaths and side effects would have been pulled from the market immediately. . 10.Kartnig, Theodor, Franz Still, and Franz Reinthaler. Pure suramin is colorless when dissolved in water or saline as a 10% solution (100 mg/mL). Regarding our own experiment with natural antipurinergic therapy, we've been trialing Kudzu for the past three weeks and the outcome has been pretty impressive. Still, I do drink it occasionally. Dont forget to also check what else you need to do to build your immune system strong it will be more than worth it in the end. i just emailed a well known ME/CFS doctor i know (who wishes to remain anonymous) with the names of the two herbs/supplements mentioned at the top of this thread, and he said: "I have talked with every prominent herbalist I know to see if there is a similar substance out there, and so far, nothing.". Journal of clinical oncology 10, no. please let me know if you try the two you mentioned at the start of this thread. 10. Thank you Lizzy for sharing this with us so much appreciated. Our bodies are built in such a way they can withstand being treated badly for a time, but it doesnt go on forever. Identification and evaluation of the inhibitory effect of "Suramin: a novel growth factor antagonist with activity in hormone-refractory metastatic prostate cancer. 13. "Antimicrobial activity of the essential oil of young pine shoots (Picea abies L.). There are so many wonderful natural medicines in the world. Researcher Dr Robert Naviaux of the San Diego School of Medicine gave suramin, a drug first developed in 1916, to 10 autistic boys between the ages of five and 14, and noted transformative results. If you have any healthcare-related concerns, please call or see your physician or other qualified healthcare provider. Korean Journal of Veterinary Research 33, no. Quoting from our 2017 publication,Like many intravenous drugs, when administered improperly by untrained personnel, at the wrong dose and schedule, without careful measurement of drug levels and monitoring for toxicity, suramin can cause harm. I do seek scientific confirmation of the safety and effectiveness of the herbs and remedies I use. The natural alternative of Suramin - and the original compound is found in Eastern White Pine (pinus strobus) needles. , But I know that people have sprayed round up around their yards on dandelions and thistles. Of-course its going to react. And the raw milk has special nutrients, that pasteurization kills, so it has to be raw milk to work. "Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin. Wormwood is one of the most effective antiparasitic herbs in the world, and one of the best natural alternatives to Ivermectin. Nattokinase (proteolytic enzyme) has a history of being used to, Giant Hyssop or Horsemint (Agastache urtifolia), Wheatgrass and Wheatgrass Juice (the young blades). They do change our DNA in the sense that they take it back to how it was when we were a baby. Suramin | C51H40N6O23S6 | CID 5361 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. The mark of the evil one is this: when people sell their souls to the devil by participating in ghastly human and ch/ild sa/crifice so they can obtain more power, finances and fame. Suramin. National Institutes of Health. Suramin is approximately 99-98% protein bound in the serum and has a half-life of 4178 days average of 50 days; however, the pharmacokinetics of suramin can vary substantially between individual patients. The first shoots used to be used as a spring tonic many years ago. Other P2X receptors are inhibited by H+ ions, so that acidic conditions greatly reduce the potency of extracellular ATP. ! 6 (1992): 881-889. "Understanding the mechanism of the antimitogenic activity of suramin. Try to put aside your previous teaching and open your spirit to receive from God. I haven't seen night awake or silly giggling in the middle of the night since he started Kudzu. Suramin (as mentioned by Dr Judy Mikovits, PhD) and Shikimic acid are both found within the needles of the common pine tree. Since a lowered pHe is also known to enhance agonist activity at P2X receptors on sensory neurones containing P2X2 transcripts, the sensitization by metabolic acidosis of native P2X receptors containing P2X2 subunits may have a significant effect on purinergic cell-to-cell signalling. These data indicate that sgp130 inhibits the LPS-induced IL-6 trans-signal and show IL-6 and its receptor are involved in maintaining sickness behavior. [6] In the United States it can be acquired from the Centers for Disease Control (CDC). Aug 12, 2017 . Pine Needle Tea 101: Health Benefits, Properties, and Uses - BalkanHerb We envision a shelf-full of related drugs, a toolkit of devices, and a suite of new autonomic balancing, cognitive and behavioral therapies that can be matched to each patient and each disease. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Happy researching. Potential Suramin Alternatives - Sytrinol and Kudzu (Anti Purinergic Therapy) . But it would be fine to do both. Douglas fir is ok, white pine is ok. Hi Marilyn Low-dose PAX-101 improves autism spectrum disorder symptoms in - Healio Whatever you do DO NOT use radiata pine needles, they are toxic. Suramin (Injection Route) Description and Brand Names - Mayo Clinic It is illegal to use suramin in humans for any purpose in the US except in FDA-approved clinical trials. De Clercq, Erik. Sent in accordance with our Privacy Policy. The chemical structure of suramin was kept secret by Bayer for commercial and strategic reasons, but it was elucidated and published in 1924 by Ernest Fourneau and his team at the Pasteur Institute. "Efficient reversion of simian sarcoma virus-transformation and inhibition of growth factor-induced mitogenesis by suramin." [11], Less common side effects include extreme fatigue, ulcers in the mouth, and painful tender glands in the neck, armpits and groin. I buy my oil fromdoTerrabecause of its superior grade. ", 20. Xu, H. Eric, Wanchao Yin, Xiaodong Luan, Zhihai Li, Leike Zhang, Ziwei Zhou, Minqi Gao et al. I dont know but I do know that God will provide. ", 21. 9. I have bought this before for myself just for good health. Curcumin nanosystems could be powerful COVID-19 therapeutics interesting! I will strengthen you and help you; I will uphold you with my righteous right hand.~Isaiah 41:10, Deep Roots At Home now has a PODCAST! 'Game-changer for autism': 100-year-old drug reverses symptoms - RT Intramuscular and subcutaneous administration could result in local tissue inflammation or necrosis[citation needed]. You must log in or register to reply here. You can alsofind me onInstagram,Truth Social(a new free-speech conservative channel), MeWe andTelegram. I'm not too concerned about Il-6 being a problem in CFS but I've thought about that receptor a bit. All rights reserved / Site by, Post-treatment Lyme disease syndrome (PTLDS), Post-coccidiomycosis (Valley fever) chronic fatigue syndrome, Treatment-Resistant Major Depressive Disorder with suicidal ideation, NARP, Leigh, and other Primary Mitochondrial Diseases, Post-chemotherapy cognitive impairment, fragility, and accelerated aging symptoms, Chronic pain syndromes in children and adults, Drug addiction recovery therapy, e.g., opioid addiction with hyperkatifeia, Treatment-resistant, post-COVID long-haulers with multisystem chronic fatigue syndrome, Severe Obsessive-Compulsive Disorder (OCD), Pediatric acute-onset neuropsychiatric syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS), As an additive in organ transplant media to improve organ survival, and decrease inflammation and rejection, Subacute-chronic traumatic brain injury (TBI), Postural orthostatic tachycardia syndrome (POTS)/Dysautonomia. Yes, those pesky little yellow flowers that seem to love gracing the best of lawns! Kudzu is one although it is not as potent. An alternative to synthetic drugs is the search for anti-parasitic plant extracts or secondary metabolites derived from them. The all natural form of suramin might be licorice root, NAC,vitamin C , green tea. Bumping this to see if anyone's benefited from high dose Kudzu, Good question, I don't have a good answer, though someone with more scientific knowledge than me could probably calculate it using the paper cited above, I'd be remiss if I didn't post this Kudzu precaution literature. You cannot continue to consume fake foods, day in and day out, and for your body not to react to it. ". Suramin inhibits chikungunya virus replication through multiple mechanisms. Suramin was shown to be safe and effective in three preclinical models of ASD9-11 and a small human clinical trial1 in peer-reviewed papers published between 2013-2017. [3] It is given by injection into a vein. ", 22. The active ingredients in wormwood are toxic to most types of intestinal worms, including Giardia lamblia, a parasite responsible for giardiasis. Suramin Definition. To evaluate the localization of this presumed alcohol binding site, the effect of the intracellular application of ethanol was studied on the inhibition of ATP-activated current by extracellularly applied ethanol. Janet Ossebaard is one from The Fall of the Cab/al series. (3) This study also says suramin doesn't work well on p2x4. It is still early to say but maybe this will enter the top three interventions. Regarding our own experiment with natural antipurinergic therapy, we've been trialing Kudzu for the past three weeks and the outcome has been pretty impressive. Naviaux Lab, 2023. According to credible, published research from scientists in Spain from La Quinta Columna, somebut not allinjections, appear to contain high levels of graphene oxide while some appear to be saline placebos. And this video discusses the findings of graphene oxide and how it sets into motion a whole cascade of inflammatory responses and cell death in you or a loved one. Further investigation of the herb reveals a study (Smith . Maybe This Really Is the Antidote to The Covid Vaccine Contagion Thank you, Jo . Thank you!). The respective distribution of glycosome volumes and for cells treated for 72 h with suramin is shown as a bar graph. It is not found in pine needles and cannot be found in any herbal teas. [10], Suramin has been applied clinically to HIV/AIDS patients resulting in a significant number of fatal occurrences and as a result the application of this molecule was abandoned for this condition. 1 (1987): 143-148. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. A polyanionic compound with an unknown mechanism of action. Kudzu has been shown to be an agonist of the P2X7 receptor (. "Suramin in the treatment of AIDS: mechanism of action." But, I would research it to the uttermost if I were you! 6. anyone with more of a brain than me have any ideas? For a better experience, please enable JavaScript in your browser before proceeding. Maca Root 8050mg Per Caps, 4 Months' Supply Supports Reproductive Health Natural. And this gem of a video by Judy Mikovits. Several P2Y12 inhibitors are approved to treat heart disease, but other purinergic receptors are likely to be more important in ASD. These people invite evil spirits to come into them and tell the HS He must depart! Within minutes, behavior returned to normal. or Best Offer. Stinging nettle can be found online and at health food stores. [15], The mechanism of action for suramin is unclear, but it is thought that parasites are able to selectively uptake suramin via receptor-mediated endocytosis of drug that is bound to low-density lipoproteins and, to a lesser extent, other serum proteins. ", 19. God always has the answer! Suramin is 20 or more times as powerful as remdesivir, which is the only currently approved anti-COVID-19 drug. Interesting info Martin! Suramin shows promise as COVID-19 treatment - News-Medical.net In addition, pharmaceutical grade suramin is hard to make. https://www.biorxiv.org/content/10.1101/2020.10.06.328336v1, 3. The differences are about 20% higher. 1! For more information, please see our FAQ. Enlighten yourself - become aware of what is pulling your health down on a daily basis and what to do about it! Suramin is used in the treatment of African sleeping sickness (African trypanosomiasis) and river blindness (onchocerciasis), infections caused by parasites. Betsholtz, Christer, Ann Johnsson, Carl-Henrik Heldin, and Bengt Westermark. 2. Pine needle tea (obviously nothing poisonous as most pine nuts (from all pine cones ) are edible but some are poisonous she was just covering her ass so to speak ppl have been makin this kinda tea for ages it has high vitamin c and has been used against scurvy for Mariners for 1000s of years, Do you know if the dandylion, star anise, fennel or pine needles have to be in tea or heated to release the suramin? 15.Mooon, Jeong-jo, Young-bok Han, and Jin-suk Kim. I love the way she says that they wouldnt be injecting people unless they already knew what could be done to reverse it. [1][2] It is the treatment of choice for sleeping sickness without central nervous system involvement. A lawn treated with Roundup would also have no grass, as well as no dandelions, no anything. Is Pine Needle Tea, Suramin, & Shakimic Acid The Answer To Covid Maybe they have never moved on past their time in the womb and need to be wrapped and snug. what about plavix? Using remedies is a personal decision. The autistic boys were randomized to receive either one intravenous infusion of low-dose suramin or a placebo infusion. @Jesse2233 but i think you are on the right track, as almost every medication is based on a "natural" supplement/herb. Zoltner, Martin, Gustavo D. Campagnaro, Gergana Taleva, Alana Burrell, Michela Cerone, Ka-Fai Leung, Fiona Achcar et al. A few Dandelion leaves in salads are good, and Fennel is great to eat. Alcohol, well Ethanol, is not a p2x antagonist. Are You Sleeping in Scary, Toxic Contaminated Air? i wish i could grasp what this means, as it states both suramin and plavix in one study. Current status of the nomenclature and properties of P2X receptors and their subunits", "Use-dependent inhibition of the skeletal muscle ryanodine receptor by the suramin analogue NF676", "Quality of life impact of three different doses of suramin in patients with metastatic hormone-refractory prostate carcinoma: results of Intergroup O159/Cancer and Leukemia Group B 9480", Scott LaFee and Heather Buschman.
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